It will be one of the earliest start dates for Major League Baseball and the Minnesota Twins when teams open the 2025 season.

The Twins hope to avoid snowbanks and windchills, beginning the season in St. Louis agains the Cardinals at Busch Stadium on March 27. This will be Minnesota’s second ever against a National League foe after previously playing at Milwaukee to start the 2021 campaign.


Fans may still have to pull out a few extra layers when the Twins host Houston at Target Field on Thursday, April 3, marking Minnesota’s second Home Opener vs. the Astros.  
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A pair of National League teams will have an even earlier start date as the Los Angeles Dodgers and Shohei Ohtani open the 2025 season in Tokyo against the Chicago Cubs on March 18, and the Athletics will start the home portion of their first season in Sacramento against the Cubs on March 31. 

 

New for 2025 each team will play six games against its prime interleague rival instead of four, increasing matchups between the New York Yankees and Mets, Dodgers and Los Angeles Angels, Cubs and Chicago White Sox, and Athletics and San Francisco Giants.

Something else for the Twins fan experience this season, Minnesota and the Milwaukee Brewers will play a pair of three-game Border Battle sets, with Minnesota visiting American Family Field on May 16-18 as part of MLB’s new “Rivalry Weekend” showcase. The Brewers play at Target Field from June 20-22.


Begin planning a vacation to include a Twins game by downloading your 2025 Minnesota Twins schedule here.

LOOK: MLB history from the year you were born

Stacker compiled key moments from Major League Baseball's history over the past 100 years. Using a variety of sources from Major League Baseball (MLB) record books, the Baseball Hall of Fame, and audio and video from events, we've listed the iconic moments that shaped a sport and a nation. Read through to find out what happened in MLB history the year you were born.

Gallery Credit: Seth Berkman

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